Weekly Digest - January 2025

Weekly Digest - January 2025

20 Jan 2025: GI Innovation, LaNova Medicines sign MOU to develop combination therapy for pancreatic cancer 

  • GI Innovation & LaNova signed MOU to develop a pancreatic cancer combination therapy with the immuno-oncology drug GI-102 and ADC LM-302 targeting Claudin18.2 
  • Preclinical models for pancreatic cancer showed promising anti-cancer activity
  • LaNova is known for licensing LM-305 to AstraZeneca for 800 billion and LM-299 to MSD for 4.6 trillion 
  • GI-102 enhances immune memory and LM-302 destroys tumor cells, improving response and survival 
  • The collaboration aims to advance clinical development of the combination therapy for advanced pancreatic cancer patients

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