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Archive - August 2020

ADC Digest - August 2020

ADC Digest - August 2020

Antibody–drug conjugates (ADCs)

ADC ‘s are the next generation “targetted” missiles being built in different shapes and forms to attack the enemy in a multitude of ways. What is an ADC – its is a monoclonal antibody tethered to a payload via a chemical linker. They lack the complexity of CAR-Ts, but have their own “improvement” areas. It will be a new weapon in our armamentarium. In the span of 2 weeks we saw both GlaxoSmithKline and AstraZeneca moving ahead with their ADC programs. Read more, tile wise below

Regulatory
JSKN003 granted another breakthrough therapy designation in China for the treatment of patients with HER2-positive...
24 October 2025
Regulatory
Padcev (Enfortumab vedotin) plus Keytruda (Pembrolizumab) sBLA granted FDA priority review for treatment of certain...
24 October 2025
Regulatory
Heidelberg Pharma’s lead ADC Candidate HDP-101 granted fast track designation by US FDA for the...
24 October 2025
Regulatory
AbbVie submits Biologics License Application (BLA) to U.S. FDA for Pivekimab sunirine (PVEK) an...
3 October 2025
Regulatory
Enhertu followed by THP supplemental biologics license application accepted in the U.S. for patients with...
3 October 2025
Regulatory
Henlius receives the NMPA IND approval for Its PD-L1 targeting ADC HLX43 in combination with...
3 October 2025

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