Weekly Digest - 13-19 May 2023

Weekly Digest - 13-19 May 2023

May 17, 2023: TAGRISSO (Osimertinib) (IV) / EGFRm NSCLC / AstraZeneca: Positive data from Phase 3 FLAURA2 study

  • AstraZeneca reported positive topline data from, the Phase 3 FLAURA2 study of TAGRISSO + Chemo combo in patients with Stage IIIB-IIIC or metastatic Stage IV EGFR NSCLC

  • This combination demonstrated statistically significant and clinically meaningful and strong improvement in progression-free survival

  • The safety results and the rate of discontinuation due to adverse events were consistent

  • OS data were immature at the time of analysis

  • Results support the potential for a new treatment option that builds on the benefit of first-line standard-of-care TAGRISSO monotherapy

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