Weekly Digest - September 2024

Weekly Digest - September 2024

3 Sep 2024: Avenzo Therapeutics partners with Gilead Sciences for clinical study to evaluate AVZO-021 and Trodelvy in HR+/HER2- Metastatic Breast Cancer

  • Avenzo Therapeutics and Gilead Sciences have entered a collaboration to evaluate AVZO-021, a CDK2 inhibitor, in combination with Gilead’s Trop-2 directed ADC, Trodelvy
  • The combination will be assessed in a Phase 1/2 study for HR+/HER2- metastatic breast cancer
  • Avenzo will sponsor the trial and Gilead will provide Trodelvy and the combination cohorts are set to begin in Q4 2024
  • Both companies will retain development and commercial rights for their respective compounds

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