Weekly Digest - November 2024
CAR-T Digest - August 2020
CAR-T Digest - August 2020
CAR-T Digest - August 2020
CAR-T Digest - August 2020
Weekly Digest - November 2024
06 Nov 2024: Celltrion unveils development of two cancer drugs
- Celltrion unveiled two new ADC candidates, CT-P70 and CT-P71, at the World ADC 2024 conference, marking its first public disclosure of its ADC pipeline
- CT-P70 targets cMET in non-small cell lung cancer (NSCLC) and other solid tumors, while CT-P71 targets nectin-4 in bladder cancer and other solid tumors
- Preclinical data showed CT-P70 effectively suppressed tumors in cMET-expressing models with better safety and performance than MMAE-based ADCs. CT-P71 demonstrated strong tumor suppression in bladder, breast, and lung cancers, with an improved safety profile over current nectin-4 targeting ADCs
