07 May 2026: InnoCare Pharma’s independently developed CDH17-targeted ADC innovative drug ICP B208 has been approved for clinical trials
InnoCare Pharma has expanded its ADC pipeline after receiving National Medical Products Administration approval for clinical testing of its CDH17-targeted ADC ICP-B208, marking the company’s second internally developed ADC to enter the clinic
ICP-B208 is designed to target CDH17-expressing tumors with a potent cytotoxic payload, with preclinical data demonstrating encouraging antitumor activity across multiple gastrointestinal cancer models
The program enters a rapidly growing area of interest, as CDH17 is highly expressed across multiple gastrointestinal cancers and is increasingly viewed as a promising next-generation ADC target with no approved therapies currently available
With ICP-B208 now moving into clinical evaluation, InnoCare continues to position itself among the emerging Chinese biotech players advancing next-generation ADC innovation in solid tumors