Weekly Digest - Feb 2024

Weekly Digest - Feb 2024

15 Feb 2024: Lantern Pharma progresses novel ADC program in various solid tumors

  • Lantern has advanced the development, synthesis, and preclinical POC of a novel, highly potent, cryptophycin-based ADC
  • The company has leveraged RADR, a proprietary AI platform for target selection and molecular payload characterization in ADCs, and a unique, controlled conjugation approach for maximizing DAR ratios while controlling for non-specific conjugation
  • Lantern expects to move towards IND development of the ADC program during 2024 with a focus on select solid tumors that are unresponsive or refractory to current therapies
  • ADCs, a promising cancer therapy class, are projected to surpass $24 billion in revenue by 2030. Recent M&A activity reflects their importance, with both emerging biotechs and global pharmaceutical companies heavily involved

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