Weekly Digest - April 2024

10 Apr 2024: Merck’s $208m acquisition of Abceutics aims to enhance ADC safety

  • Merck & Co. acquired UB’s spinout, Abceutics, for $208 million to enhance ADC safety
  • The deal included contingent milestone payments and gave Merck access to Abceutics’ payload-binding selectivity enhancer (PBSE) technology
  • PBSE technology works to neutralize and stray payload molecules to reduce the impact on healthy cells, may optimize selectivity and efficacy
  • In January, Merck acquired Harpoon Therapeutics and its T-cell engagers for $680 million

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