Weekly Digest - 20-26 May 2023

Weekly Digest - 20-26 May 2023

May 24, 2023: Sitravatinib (IV) / Nivolumab (Opdivo) (IV) / NSCLC / Mirati Therapeutics: Phase 3 SAPPHIRE study did not meet the primary endpoint of overall survival

  • The Phase 3 SAPPHIRE study did not meet the primary endpoint of overall survival in the final analysis
  • SAPPHIRE is a Phase 3 study evaluating Sitravatinib in combination with Nivolumab vs Docetaxel in patients with 2L/3L NSQ-NSCLC, progressed on prior therapy with chemotherapy and immune checkpoint inhibitor therapy
  • The company planned to disclose the study data at a future date

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