Weekly Digest - January 2025

Weekly Digest - January 2025

27 Jan 2025: Innate Pharma announces first patient dosed in phase 1 study of its Nectin-4 targeting antibody drug conjugate IPH4502 in selected advanced solid tumors

  • Innate Pharma began a Phase 1 study (NCT06781983) of IPH4502 in solid tumors. The study has two parts: dose escalation and dose optimization part, enrolling approximately 105 patients

  • IPH4502 targets Nectin-4 in solid tumors. Tumors targeted include urothelial carcinoma, non-small cell lung, breast, ovarian, gastric, esophageal, and colorectal cancers but not limited to it

  • Innate Pharma views the trial as a milestone in advancing targeted ADC therapies

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