Weekly Digest - September 2024

Weekly Digest - September 2024

24 Sep 2024: Pinotbio Secures Milestone Payment Following Celltrion’s Execution of ADC Platform Technology Option

  • Pinotbio is set to receive a milestone payment from Celltrion after the latter chose to continue R&D on two drug candidates using Pinotbio’s ADC platform, PINOT-ADC
  • The milestone payment is the first agreement signed in October 2022, where Celltrion secured options to use the PINOT-ADC technology for up to 15 cancer targets
  • Celltrion initially paid an upfront fee of 1 billion won ($749,175) and could lead to a total of about $1.2 billion in payments if all options are exercised, including advance payments and milestones
  • The PINOT-ADC platform offers next-generation ADC technology designed to improve safety and efficacy, utilizing a novel Camptothecin derivative for payload and cleavable linker technology
  • Company expressed confidence in the platform’s capability to meet Celltrion’s standards and emphasized the intention to collaborate closely for generating additional revenue and enhancing company value

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