Weekly Digest - May 2026

Weekly Digest - May 2026

29 April 2026: Tacalyx secures €11 million to advance lead TACA-targeting ADC programme toward the clinic

  • Tacalyx announced the selection of its first clinical candidate, TCX-201, an antibody drug conjugate targeting tumour-associated carbohydrate antigens (TACAs), with plans to advance the program toward clinical development and file a clinical trial application in 2027
  • The company also secured €11 million in a seed extension financing round from existing investors to support preclinical development of TCX-201 and advance its broader oncology pipeline
  • TCX-201 is being developed for gastrointestinal malignancies and other solid tumors, leveraging Tacalyx’s proprietary platform designed to target TACAs, a novel and largely untapped class of tumor-associated antigens
  • The funding will further enable progression of additional pipeline assets, with the next clinical candidate selection expected by the end of 2026, as the company transitions toward becoming a clinical-stage biotech

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